The Jacks Lab advances our understanding and the treatment of cancer using genetically engineered mouse models.
Click the organs to learn more about the mouse models that are currently being used in the lab.
Understanding how common injuries to the colon influence cancer initiation and progression
Identifying novel antigens to develop immune therapies to treat osteosarcoma.
Determining cell intrinsic and cell extrinsic influences on tumor progression and evolution.
Characterizing PDAC cancer evolution and progression using sophisticated mouse models to further understand the tumor microenvironment and improve treatments.

Tyler Jacks is a Daniel K. Ludwig Scholar and David H. Koch Professor of Biology at MIT. Our studies are supported by a mixture of various sources including the National Institutes of Health, Ludwig Fund for Cancer Research, Lustgarten Foundation, and Koch Institute for Integrative Cancer Research.
Value Statement
The Jacks Lab encourages highly talented and motivated individuals of all backgrounds to join us in pushing the boundaries in what we can achieve in cancer research. In partnership with the MIT community, we strive to train all lab members to reach their full potential and contribute to our understanding of cancer and new ways to detect and effectively treat the disease. If you are interested in joining the lab as a postdoctoral fellow, please send your CV/Resume to Dr. Tyler Jacks. If you are interested in being a graduate student in the lab, please apply to the Biology Graduate Program (https://biology.mit.edu/graduate/).
Publications
Recent publications include: