Recent Papers:
-
Clonal hematopoiesis in lung adenocarcinoma pathogenesis.
Parisi T, Santibanez Ocampo B, Adelman J, Cai Y, McConkey M, Gibson CJ, Ebert BL, Miller P, Jacks T. JCI Insight. 2026 May 8;11(9):e203981. doi: 10.1172/jci.insight.203981. eCollection 2026 May 8.PMID: 42100867Free PMC article.
Intrinsic electrical activity drives small-cell lung cancer progression
Peinado P, Stazi M, Ballabio C, Margineanu MB, Li Z, Colón CI, Hsieh MS, Pal Choudhuri S, Stastny V, Hamilton S, Le Marois A, Collingridge J, Conrad L, Chen Y, Ng SR, Magendantz M, Bhutkar A, Chen JS, Sahai E, Drapkin BJ, Jacks T, Vander Heiden MG, Kopanitsa MV, Robinson HPC, Li L. Nature. 2025 Mar;639(8055):765-775. doi: 10.1038/s41586-024-08575-7. Epub 2025 Feb 12.PMID: 39939778Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads
Lussier DM, Alspach E, Ward JP, Miceli AP, Runci D, White JM, Mpoy C, Arthur CD, Kohlmiller HN, Jacks T, Artyomov MN, Rogers BE, Schreiber RD. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2102611118. doi: 10.1073/pnas.2102611118. PMID: 34099555. -
Clonal hematopoiesis in lung adenocarcinoma pathogenesis.
Parisi T, Santibanez Ocampo B, Adelman J, Cai Y, McConkey M, Gibson CJ, Ebert BL, Miller P, Jacks T. JCI Insight. 2026 May 8;11(9):e203981. doi: 10.1172/jci.insight.203981. eCollection 2026 May 8.PMID: 42100867Free PMC article.
Intrinsic electrical activity drives small-cell lung cancer progression
Peinado P, Stazi M, Ballabio C, Margineanu MB, Li Z, Colón CI, Hsieh MS, Pal Choudhuri S, Stastny V, Hamilton S, Le Marois A, Collingridge J, Conrad L, Chen Y, Ng SR, Magendantz M, Bhutkar A, Chen JS, Sahai E, Drapkin BJ, Jacks T, Vander Heiden MG, Kopanitsa MV, Robinson HPC, Li L. Nature. 2025 Mar;639(8055):765-775. doi: 10.1038/s41586-024-08575-7. Epub 2025 Feb 12.PMID: 39939778Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration
Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, Clare Beytagh M, Xuan L, Feldser DM, Hemann MT, Zamudio J, Dimitrova N, Letai A, Jacks T. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2019740118. doi: 10.1073/pnas.2019740118. PMID: 34074758 -
Clonal hematopoiesis in lung adenocarcinoma pathogenesis.
Parisi T, Santibanez Ocampo B, Adelman J, Cai Y, McConkey M, Gibson CJ, Ebert BL, Miller P, Jacks T. JCI Insight. 2026 May 8;11(9):e203981. doi: 10.1172/jci.insight.203981. eCollection 2026 May 8.PMID: 42100867Free PMC article.
Intrinsic electrical activity drives small-cell lung cancer progression
Peinado P, Stazi M, Ballabio C, Margineanu MB, Li Z, Colón CI, Hsieh MS, Pal Choudhuri S, Stastny V, Hamilton S, Le Marois A, Collingridge J, Conrad L, Chen Y, Ng SR, Magendantz M, Bhutkar A, Chen JS, Sahai E, Drapkin BJ, Jacks T, Vander Heiden MG, Kopanitsa MV, Robinson HPC, Li L. Nature. 2025 Mar;639(8055):765-775. doi: 10.1038/s41586-024-08575-7. Epub 2025 Feb 12.PMID: 39939778Pan-Cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection
Guo JA, Hoffman HI, Shroff SG, Chen P, Hwang PG, Kim DY, Kim DW, Cheng SW, Zhao D, Mahal BA, Alshalalfa M, Niemierko A, Wo JY, Loeffler JS, Fernandez-Del Castillo C, Jacks T, Aguirre AJ, Hong TS, Mino-Kenudson M, Hwang WL. Clin Cancer Res. 2021 May 15;27(10):2807-2815. doi: 10.1158/1078-0432.CCR-20-4382. Epub 2021 Feb 25. PMID: 33632928